Mass photometry
A rapid detection of protein particle distribution
Mass photometer from Refeyn and sample data
Benefits:
measures true molecular mass
shows molecular heterogeneity
works in solution
uses minimal amounts of sample
no modifications
Applications:
Measuring the molecular mass of single biomolecules
Measuring the oligomerization state
Screening buffer conditions
Characterizing sample heterogeneity
Monitoring sample components'stability
Studying biomolecular interactions
Mass photometry application in ApoFerritin gene to structure workflow
CAC detection (Critical aggregation concentration)
-
1000µM Thalidomide
No aggregation
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20µM Clotrimazole
Strong aggregation
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Biophysical Assays
